产品货号：
Z29137
中文名称：
TP53AIP1抗体
英文名称：
Anti-TP53AIP1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TP53AIP1 Antibody |
| 指标别名 | p53-regulated apoptosis-inducing protein 1;p53AIP1;TP53AIP1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | TP53AIP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | p53AIP1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human p53AIP1.The immunogen is located within the first 50 amino acids of p53AIP1. |
| 计算分子量 | 13kDa |
| 成分 | p53AIP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | p53AIP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor protein can induce apoptosis through transcriptional activation of several genes.One such protein p53AIP was initially identified through direct cloning of p53 binding sequences from human genomic DNA.Its expression is inducible by p53 following p53 phosphorylation on Ser-46,and ectopic expression of p53AIP leads to apoptotic cell death.Both the phosphorylation of p53 and the induction of p53AIP were blocked by inhibiting the expression of p53DINP1 by the introduction of antisense oligonucleotides to p53DINP1,suggesting that the apoptosis associated with p53AIP expression is regulated by p53DINP1.Finally,as adenovirus-mediated introduction of p53AIP has been shown to suppress tumor growth in vivo,it has been suggested that p53AIP gene transfer may become a useful strategy for the treatment of p53-resistant cancers.Three isoforms of p53AIP are known to exist;this antibody will detect all three. |
| Uniprot ID | Q9HCN2 |
| 基因名全称 | Tumor protein p53 regulated apoptosis inducing protein 1 |
| 蛋白名全称 | Tumor protein p53 regulated apoptosis inducing protein 1 |
| 推荐稀释比 | p53AIP1 antibody can be used for detection of p53AIP1 by Western blot at 4 ～ 8μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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